What if Jenner's smallpox vaccine had gone differently?

Cowpox inoculation gives reliable protection against a disease that killed one in ten.

If it had gone differently: Smallpox keeps culling children into the 20th century; the very idea of a vaccine arrives late.

The real history on Wikipedia ↗

Later turning points that leaned on Jenner's smallpox vaccine. Change it in the game and the ripples reach all of these.

1. 1740Europe's population boom. Without it, Without a surplus of hands and mouths, there is no cheap urban workforce waiting for the factories.