What if the rise of the Ottoman Empire had gone differently?

The Ottomans consolidate an empire straddling the land routes between Europe and Asia.

If it had gone differently: The eastern Mediterranean stays contested and open; no single power can tax or close the road to the East.

1. 1453The fall of Constantinople, The Mediterranean spice routes stay open and cheap; no one in Iberia is desperate enough to gamble on the open ocean.
2. 1498The sea route to India, Europe's trade with Asia stays overland and heavily taxed; the seaborne empires of the Dutch and English have no template.